Wade steps outside, confused, but the man in the helicopter tells him that he is Dr. Just then, a helicopter flies next to the apartment building, and a man in the helicopter shouts through a megaphone for Wade Wilson to step outside. Wade says that she should leave him, saying that she deserves better than him, but Vanessa refuses. Wade tells her his bad news, and she starts crying and asks him what they'll do.

Waiting for him at his apartment is Vanessa Carlysle, a shapeshifting mutant who Wade has been secretly living with. Wade storms out of the building and runs home, angry. After entering the doctor's office, Wade is told he has inoperable cancer, and he has months to live. As Wade gets up from the fall, Deadpool's narration explains that he was called to his doctor's office at night, and that whatever it was for, it couldn't be good. At this point, Deadpool narrates, explaining to us that back then, he became a minor mercenary after his mother died of cancer, his father got drunk and got shot, his step-father left him, and he was kicked out of the United States Army Special Forces for unknown reasons. Eventually, we see Wade attempt to jump to another rooftop, only to fall, hit the side of the other building, land on a dumpster and get laughed at by a homeless man. The scene is narrated by Wade Wilson himself, as are other parts of the movie. The film begins in a pre-credits scene, in which Wade Wilson (played by Ryan Reynolds) in street clothes is running across a rooftop in an unknown city at night.

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